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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '66da8ec98a987b469e2809b800bc9a6f21f6a37bbca897ded09029c136886109' 
  AND token = 'JYgkxvnFuijLBmGHL8L5qcI8GH0VAnNG3MNbnpgDVBo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}