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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '0161ff8e2888649023adef5c1f4460b206942f23e7f471e177d84d2c666e4fd5' 
  AND token = 'gDf+L1m3/p38rvAZtH+fV1E3S/TzXBaxhop0/WeEO4c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}