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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '53f8edd94ce35e50f13c80b48ffd8460c92e2e4d2c1069189f14c65343c9344c' 
  AND token = '/k/UPOi748+bIvqF/WlrdTejobF6OgwEo4wvvJ8lYSE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}