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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '10ed26e7c9953ab690658a1b0faa0c3b6df3bb233ec68d3182615e40c9012f20' 
  AND token = 'h4KuhFLa/OpW3tyhf+E6dKSYb5XyNJicCvS1I6N9ZrE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}