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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'e7b45ae9479552178c91ac36a0ff80057f571d64a1a94172f641fe047335a406' 
  AND token = 'tY/1So98+R21Q2+Q2cjr2eHFBS0GnF1bjFopif4+qKY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}