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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '491e4cf888e06f4f862d9e15fd89a29ecc11cfe8520dcc6316731d07d5875d45' 
  AND token = 'rcY/8oQDPhM60i1WmsWo5kno+mujGnID6vJ2JRmRyX0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}