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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'dffa034ab3c04798fdbc84a305d16ed0bc34ed271dc5389882d2e1587187548c' 
  AND token = 'YZkEGRy+Z1PxuZg4W0gvPpggxirzd78iSX9AE+as7SM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}