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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '4cfe8e89a8378bc331e15e03d8cd2e0aa6b0e8d5f86a7fb121ee7717b5fc0225' 
  AND token = 'TusUOVpl63OhabiPMIHSZYtEM9JlTceVygOKMIH2eSA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}