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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '4a0656703f0613c48f718e685e0747db9f66d464faeaf739dcdadab740a9fc23' 
  AND token = 'VPuIcc4y+GIef04aTLVpD3+7HfcZ5p8JegQsmKewYyQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}