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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '2424c6397df7bd27400296ffdca158d385cf27e048fd8f3fa85310df1aa2aa5b' 
  AND token = 'N57ooqwlinCmNpwkQk846mzloDjQW2xeHHCNdx2wKfc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}