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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'd623103ca7d2d92ae08e4acadf8b1d04e3be8289c1f0a483b8821af773181b67' 
  AND token = '3SLJBKYCxuvugAKsZ3JKV2eM2rBO4Z3L8/fSe/XF/AA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}