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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'ba59454abc1fbab800ecf644555568f4951e372887829826fe13de6854baac33' 
  AND token = 'E2WgaC3G6K8cV5Jq+VEadNPHH2J0VL99260/+Dm3c2w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}