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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'cd63538716c2a280e8977e1d903b16cc71e276b5c95155ed93457723beca9226' 
  AND token = 'GZiObvXO9RP80e5cClNoxIQbj8WapWbSWSTLhLdAEVM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}