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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'ed5b20bc734f33beca10c7da376cb51f8139ea306cb4eff0818b8ab4d1700f1c' 
  AND token = 'pbs4wLHvb9CSL/HCp/vDzmm3vM+BS33Bz/4GyKReKgM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}