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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'fc1e87dd43532b8793924dc427cf8fef080ffe762ad1c8258e0edc1234d88445' 
  AND token = 'bvx9fwIDvySCFkU+hmO8Skgg4wddmiYHZij6+enYCkQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}