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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '4106f48737a8e4027b67b5b08e2a688a182ca887eeecb0dab753d9f9b76d0f39' 
  AND token = 'dpTxn9JSOu06/DdXOoHz6ImuNJ8BEnj8mVbDDx1rtZc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}