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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '0144295e9df8e95bbf87f7d3ce27050c8a54978f921c36cace05f40462e32bac' 
  AND token = 'kSKdAhmtAq9D4+HYxUYSoTtAHf6f3vax688dHa3hE1k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}