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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '1e881c63cb601f711d6166a2d6c238db5f9bba3fa852907d06a5cf30b23e159b' 
  AND token = 'GQD4Mt+NmcHVj2+5h/SeM0fWEYcsIGm0axPp4VjsoEg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}