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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '20326903ba3e6da3098c9eac78e62804a4f9e880ae62aa52491b0cb073bf87e3' 
  AND token = 'KTQMfwErq3vo/bpnQSIOPLS8HYN+pZa5/e0c1BV8UC8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}