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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '3df4033dbc8171e55698bcde0768c10d12dc53e628b05e75df9bda2b0953caf8' 
  AND token = 'cVT/azdre+V9kw48YSH3UeSa+VxOP0OJ0jbWdajeCBM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}