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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '10c9341af3c56c657db6de9f7b08381a97afe93f624b0f584dbc9e8e34b7f20d' 
  AND token = 'CJB4JaSDnOqq7SPzSkM92lvCF5aFIsofThOlz5988M0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}