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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '2ec1088b6d76a7601bfe7061d6339754b2f225f4473d1c1b4936ff931c29a915' 
  AND token = '+L5rInny9kIlNgrKl8iEf9nYh98MYjwQijt1HmNum2E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}