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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '1b4ce366ca14bd00a4f3cdad6a9602c980033f545026cb90139bbc410e8b3c3c' 
  AND token = 'HoIgeSN/wlHlrqtyHAnW77MgZXXEVCDghzqgALHmlhU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}