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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'e91727ffeec29881b894ac3808818c1659190b5255eb4da40ed7e7342e8787ff' 
  AND token = 'siybXhks4p624Zi8QEc0VExAdNsfiL1I59Xy2lEyH58=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}