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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'a50adf189600f8dfcdd45f88bb50a704ad9129b0d77affe41a07e3e230de1847' 
  AND token = 'gh1vuAusxXKFMbJnrTEb9FqSNPw8uX4is8ttd9YQwIA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}