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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '9c0005972feb96e16c7ce3cde58aa34eeb53fce191bd8317c4ea6ff3a9c7f243' 
  AND token = 'zfXFg7BDVfscuqwCY/0QpUeXvW4eTOW5tOziqS7cd9k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}