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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '63281042066c79d79a1d314afd98f8a3d321f2477e8f04b59fc71f18e569da0f' 
  AND token = 'Cdqme8a5y62TCwXD8aSEgYogYSETU40mSb/X8OgxRu8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}