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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'da581fd3d3367365b4ba7de064473ffe286bea64b57dd7e5472ee42443e2d0bd' 
  AND token = 'zCAzSBmOQzCRgJDiJDFcmHED6RCPXDNT2ELM3xIbbTg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}