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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '58edbf4c1c75b787d1ad582926495ec64a797f78430a71749ba5b8bd86df0e29' 
  AND token = 'vOwTTY12WyBZPYsksj6e8qcyAKl7qZpB7SavtXtd7+Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}