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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'a3895b7484ac9c5409cebdc161e4487e87b25725dcd447fad655661c3d36904e' 
  AND token = 'jBot/KhdPzqJUcdzXd1jrTOtnytSlWyNNMx2XyNhTyk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}