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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '74e61a736c97accfce964016d1c6d13421b391ca159a1967fda721e75631b01c' 
  AND token = 'F+qx2DTj8iQkgg5vTzOrzfbXtfLARSCIRx0KAXvF1HA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}