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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'ed79dc89fe48629915e1fbbdd1d10b4b99e29259ccb12749e9321107c165d29a' 
  AND token = 'EM8tjxY/4XupopzZfxw4103vcKzjztpkpgCSDChnArQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}