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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'caebb57116e9c1134f37293796424438034bfc45af48f37f98f3c0343dfaf0a7' 
  AND token = 'qgPIRtkI9i2tSyRxrnzLbR8C8HN7ZZNjCGsXtbsEPv4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}