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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '036196f088e6d53346df746e30fee2154207fb5ee966eb57e5bc39110f9fc0f0' 
  AND token = 'vsXvKav6Bq4JFD/D8koGyf7c3cgkpcaj9bEaMZWL8AU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}