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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '7a9435d3ec0ae215480386dafa9c1d653cfa89d98e9b78f1a06549ab14de2def' 
  AND token = 'GIFAm5+g4Zm9csCxxoFtPpuUsi0kPM9dbwk+UVgud98=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}