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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '9eb4eb419a8b37b99bed46c5be42373df107766dd30bcabe2e4f8e38dd4f66ef' 
  AND token = 'rriJByNoUbEl2G5K1Dn+ZW/2DLDfABNtTlJoe7Jfrfg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}