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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '5ad53eda2f3c1002ee4385e68907667c8cc88948a461194c5bdd70ea7b74bc1e' 
  AND token = '0ZYA5NW5gZkgWt4jLMOYTyGcUztoFxUhgxJB3xRBzMk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}