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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'f63965655ac05bc8bd3e8ed0b119418144ae42a4d6e13c51cf5d98913f288257' 
  AND token = 'PRo7PRtune281hBLcm0DwOXLSlkktbPzEo9ddxVK7Qo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}