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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '49b1b0bcaade294159f9281eab154f9049622c0d95b1efb4775a2ae5e1b159a6' 
  AND token = 'cPxndtpYplABdwmnNrUUwfORr2csnuBQtTs1E6QgVHg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}