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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'a1a0edb6ba8638c8e50022979e5669742013c1e00e2391fea5ab8c121edb84b1' 
  AND token = 'Fiqjvz+rtFlBU0F0GZrO5R2nJ7WMoIyqdlzl3Q7Glx4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}