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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '187d62f104ccaa3609bfa72cdd3d6c7b49d1ad75f9a5bab7b4b0d04096942d51' 
  AND token = 'qR1HN2b6mQnJ2iFbuzfrq+Ke+97SXa/uouP+LzRXZlg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}