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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '290ade220c76bbacc237e48db7b998be9eea2b6358f04767d4feb5df77d38e8c' 
  AND token = 'w0QHjgxkeesoDVaNWxxlpjj+wFsDMPGdgGFeOrUu9vw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}