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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '041133e88411f64be7b527c58997207e9e10c9c29a06beaa60b61f9a4fd48037' 
  AND token = 'icqX+Yda8syapuBqIau6woP014zI+sLmEdPm8UgBzWU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}