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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'e216238127a76d874c4ae4b1886244ae2a951c0269fe46f0b10e51a895fa25c0' 
  AND token = 'aV4bAOx+cSw3jsnoxtE3zbKcWSGpmZpxBo14g9vDcsA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}