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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '65a46a64695b978dae4fe9bcfc5b598295e3f9b093102ba7f11002d6f64f3096' 
  AND token = 'OOWhdPa6T2WTGoQuqnMe2YuDxJCKTN3GKNcjHOyMxUg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}