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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'b45554edd85a882dc30624fc62ea0d518e76b06a15fdc6f65518fc294f77b3a3' 
  AND token = '33rHPtrXk41SeNRlduQ3XwqfoO6wINCYVTpgJd45trM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}