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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '5f64e2f5d62d43614c15d9a13b19b9a4105bffc294c8146f63ae2aff55e288aa' 
  AND token = 'VDuBx/foqeuP+XuYR/1QgfxrmXAG2meHteYBlb1R1o8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}