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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '810b0afb87b101a3a866a73ca292220707ccd57bf18bab34ac67cc5e6a3f3779' 
  AND token = 'lyn0vp12HG2yc70tZIUsIz2yPXFwZBxYbmFnMiiUmeI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}