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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '0f43b091f081932c6bf9f7700a2193b270f602a5c5e531e3e6f781bfe7bf2bf9' 
  AND token = 'D6uji3Uuwx1hNUUeHT5f8vx/V6vQGXO5f27BR7QGqOA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}