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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'd45a8150b5abe1404dcff75abc54d020f16c8bf51c5f8c4bc54baa0c59fb410a' 
  AND token = 'CIgqND/lsc59njKs01MBAY9czbOlkb48jMxqRi2R9HE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}